Managing Cancer Risk in Dogs: A Practical Guide for Breeders
Plain-language breeding decisions when hemangiosarcoma, mast cell tumors, lymphoma, osteosarcoma or histiocytic sarcoma appear in a pedigree.
Breeder guides, literature reviews and interactive demonstrations on the genetics of canine health, organized by topic. Every document is free to read online, and most can be downloaded as a PDF.
Hemangiosarcoma, mast cell tumors, lymphoma, osteosarcoma and histiocytic sarcoma: what the genetics literature shows, and how breeders can reduce risk with estimated breeding values (EBVs).
Plain-language breeding decisions when hemangiosarcoma, mast cell tumors, lymphoma, osteosarcoma or histiocytic sarcoma appear in a pedigree.
Heritability and GWAS findings for five major canine cancers, why they are polygenic, and how EBVs can reduce cancer incidence through selection.
How estimated breeding values, and genomically enhanced EBVs, could reduce hemangiosarcoma in Golden Retrievers by identifying at-risk family lines early.
Telling hereditary from non-hereditary cataracts, what the ACVO “Blue Book” recommends, and practical breeding decisions when cataracts appear in a pedigree.
Whether to breed a dog, its offspring or its siblings when cataracts appear in the pedigree: the key decision points in plain language.
Prevalence, the hereditary posterior polar cataract, PRA-associated and other secondary cataracts, CAER exams and ACVO breeding recommendations.
Hip quality as a polygenic trait: how many genes of small effect combine to produce the range of PennHIP distraction index (DI) scores seen in a breed.
An interactive Galton board showing how PennHIP distraction index (DI) breeding values arise from many genes of small effect.