Monte Carlo analysis on a large pedigree.
EA Thompson, S Lin, AB Olshen, et al.
Genetic epidemiology, Vol. 10, pp. 677-682, 1993
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Abstract
Monte Carlo methods for linkage and segregation analysis are applied to the HGAR1 pedigree. To address these data, the methods are extended in several ways. The results are compared with those provided by PAP.
Keywords
PedigreeLipidsFemaleHumansMaleModels, GeneticGenetic Predisposition to DiseaseLikelihood FunctionsInfant, NewbornLinkage (Genetics)Monte Carlo MethodAdolescentAdultChildChild, PreschoolInfantMiddle AgedAgedHypercholesterolemiaReceptors, LDL