Inherited neurologic disorders in the dog: the science behind the solutions.

Abstract

Canine inherited neurologic diseases are clinically varied and can be congenital, neonatal, or late onset as well as progressive or stationary. Modern genetic technologies are revolutionizing the speed and efficiency with which mutations responsible for inherited neurologic disease are being identified. Clinically similar disorders can be caused by different mutations, even within a single breed, and are thus genetically distinct. DNA tests can be used by dog breeders to reduce the prevalence of inherited neurologic disorders in specific breeds and help the veterinarian diagnose disease.